About 30 hunts in with charge blade and I've improved drastically. Getting the muscle memory down and having all of the moves, charges and transitions becoming second nature made all the difference.
It's rare that it happens so perfectly, but the few times when I've loosed a fully charged shield combo directly on a monsters dumb fucking face have been euphoric. I just got done screaming "GET FUUUUUUUUUUUUUUUUUUCKED" at my 3DS while I watched one connect in slow motion on a downed Gore and it was one of the most satisfying MonHun moments I've ever had. What a fun ass weapon.
Some day I'm going to unequip the auto guard noob charm you get in the story mode and stop using that as a crutch, but today is not that day...
Using a big hit special is always the best, plus you always remember those hype as fuck moments. I had one where a A.Rath was trying to fly away and I hit him with my S.Axe's up-swing and killed it, so fucking hype.
The game's all about practice and learning the weapons and monsters. If you put the time in you'll get really good.