bitbydeath
Member
This could end badly but it is fascinating.
https://www.sciencealert.com/scientists-just-successfully-reversed-aging-of-human-cells-in-the-lab
We have been looking for ways to turn the splicing factors back on. In our new work, we showed that by treating old cells with a chemical that releases small amounts of hydrogen sulphide, we were able to increase levels of some splicing factors, and to rejuvenate old human cells.
Hydrogen sulphide is a molecule that is found naturally in our bodies and has been shown to improve several features of age-related disease in animals.
But it can be toxic in large amounts, so we needed to find a way to deliver it directly to the part of the cell where it is needed.
By using a "molecular postcode" we have been able to deliver the molecule directly to the mitochondria, the structures that produce energy in cells, where we think it acts, allowing us to use tiny doses, which are less likely to cause side effects.
We are hopeful that in using molecular tools such as this, we will be able to eventually remove senescent cells in living people, which may allow us to target multiple age-related diseases at once.
https://www.sciencealert.com/scientists-just-successfully-reversed-aging-of-human-cells-in-the-lab
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